Publications by authors named "Y Y Trunin"

Pituitary carcinoma (metastatic neuroendocrine tumor of the pituitary gland) is the pituitary tumor with confirmed craniospinal and/or systemic metastases. These tumors are extremely rare accounting for only 0.1% to 0.

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Article Synopsis
  • Craniopharyngioma (CP) is a benign tumor located mainly in the brain's chiasmatic-sellar region, with two main types: adamantinoma-like (ACP) and papillomatous (PCP), the latter mostly affecting adults.
  • The study aimed to determine the disease-free survival in adults with newly diagnosed CP based on the quality of tumor removal and the effectiveness of irradiation, using data from 398 patients over a decade.
  • Results showed that total tumor resection significantly lowers recurrence risk, while stereotactic irradiation after incomplete resection also yields favorable outcomes, with PCPs being less aggressive and less likely to recur after complete removal.
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Despite slow growth of most pituitary tumors and high rates of total resection and/or effective therapy, pituitary neoplasms are characterized by aggressive behavior with high growth rate, frequent relapses and resistance to standard treatments in 10% of cases. In modern WHO classifications of tumors of the central nervous system, endocrine and neuroendocrine tumors, the authors propose the definition «pituitary neuroendocrine tumor» instead of previous «pituitary adenoma» and «metastasizing pituitary neuroendocrine tumor» instead of «pituitary carcinoma». Currently, there are no effective prognostic markers of aggressive tumors.

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Unlabelled: Optic nerve glioma is a rather rare tumor. It predominantly arises in pediatric patients, including those with type I neurofibromatosis. This neoplasm is accompanied by decreased visual function and exophthalmos.

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Objective: Transcallosal transseptal interforniceal approach is recognized as the most appropriate route to resect sessile hypothalamic hamartomas but individuals with obliterated cavum septi pellucidi may pose difficulties to access these lesions safely.

Material And Methods: Six patients aged 8-34 years (med - 15.5) with the rather small (medial volume - 1.

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