Interleukin 6 Signalling in Heart Failure With Preserved and Reduced Ejection Fraction.

Aim: Identification of interleukin-6 (IL-6) signaling pathways in patients with chronic heart failure (CHF).

Material And Methods: The diversity of IL-6 effects is due to the presence of classical signaling and trans-signaling pathways. The study included 164 patients with CHF hospitalized for acute decompensated heart failure (ADHF), of which 129 had reduced left ventricular ejection fraction (HFrEF), and 35 had preserved ejection fraction (HFpEF).

The computational and experimental investigations of photophysical and spectroscopic properties of BF2 dipyrromethene complexes.

The electronic excited states of BF2 dipyrromethene (2BrDPM, DPMI, DPMII, PM567 and 4PhDPM) complexes were investigated using the extended multi-configuration quasi-degenerate at the second order of perturbation theory (XMCQDPT2) and the second-order approximate coupled-cluster (CC2) methods. The excitation energies calculated by CC2 are significantly overestimated by 0.42-0.