Publications by authors named "Y Uyanıkgil"
Camel milk has a unique composition that sets it apart from other types of animal milk, which has captured the interest of medical and scientific communities. Extracellular vesicles (EVs) mainly contain exosomes (Exos, 30-200 nm) and microvesicles (MVs, 200-1000 nm). Camel milk EVs, particularly Exos, which we named EVs/Exos, have arisen as a fascinating area of scientific inquiry, holding enormous potential for the future of biomedicine due to their anticancer, antibacterial, antidiabetic nephropathy, and immunostimulatory impacts.
View Article and Find Full Text PDFHistopathology of thermal effects in endoscopic ear surgery: An experimental animal study.
Laryngoscope Investig Otolaryngol
December 2024
Objective: The potential risk of thermal damage in the transcanal endoscopic ear surgery has been a concerning issue. This study aimed to investigate the histopathological effects of heat exposure of different durations in external auditory canal (EAC) skin and facial nerve tissues.
Methods: This study was conducted on 20 rabbits assigned equally to five groups according to the endoscope-transmitted heat exposure duration: Control group (no exposure), 2, 10, 15, and 30 min.
Introduction: Autism spectrum disorder (ASD) is a neurodevelopmental disorder characterized by impaired social interactions and repetitive behaviors. This study examines the effects of fenofibrate on a propionic acid (PPA)-induced rat model of ASD, focusing on behavioral changes, inflammatory markers, and histological findings.
Materials And Methods: Thirty male Wistar rats were divided into three groups: a control group, a group receiving PPA and saline, and a group treated with PPA and fenofibrate for 15 days.
Article Synopsis
- The study investigates the effects of pentoxifylline on autism-like behaviors in rat models induced by propionic acid (PPA), focusing on how it influences brain proteins and inflammatory responses.
- Thirty male Wistar albino rats were divided into three groups: a control group, a PPA group, and a PPA plus pentoxifylline group, with various treatment regimens followed by analysis of brain and blood samples.
- Results showed that pentoxifylline significantly reduced autism-like behaviors, lowered levels of the pro-inflammatory cytokine TNF-α, increased beneficial brain factors like ATP and nerve growth factor, and improved neuronal health, suggesting its potential as a neurotherapeutic agent for autism.
Purpose: Tamoxifen, a widely used drug for breast cancer treatment, is associated with adverse effects on the liver, including the development of fatty liver. This study aimed to investigate the potential protective effect of caffeine against tamoxifen-induced fatty liver in Wistar rats.
Methods: Rats were divided into normal control, tamoxifen + saline, and tamoxifen + caffeine.