Publications by authors named "Y Uejima"
Intrauterine Ureaplasma infection is associated with chorioamnionitis and preterm birth. The difficulty of detecting Ureaplasma species by conventional culture methods makes definitive diagnosis of clinical infection challenging. Thus far, quantitative tests for Ureaplasma have been performed using adult cervical samples, amniotic fluid, and pediatric bronchial secretions, but quantification of bacterial count in central nervous system infections caused by Ureaplasma species has not been unreported.
View Article and Find Full Text PDFObjectives: Voluntary health insurance (VHI) often serves a supplementary role in Europe. The ageing population and adoption of cost-sharing models in response to economic pressures raise concerns that VHI could contribute to health inequalities among older people. This study investigates the association of VHI with health outcomes among older people across 16 European countries and Israel.
View Article and Find Full Text PDFKabuki syndrome (KS) is a genetic disorder caused by gene mutations in either lysine-specific methyltransferase 2D (KMT2D) or lysine demethylase 6A (KDM6A). This congenital disorder exhibits characteristic facial features, developmental delays in psychomotor skills, and skeletal abnormalities. Moreover, it is classified as a congenital immunodeficient disorder under the category of combined immunodeficiency, leading to hypogammaglobulinemia and the onset of autoimmune diseases.
View Article and Find Full Text PDFArticle Synopsis
- * A case study of a 1-year-old girl with CMD showed that after initial Ig replacement therapy failed, increasing the dosage and switching to subcutaneous immunoglobulin (SCIG) effectively raised her IgG levels and prevented infections for a year.
- * The exact reason for low IgG levels in CMD is still not fully understood, but potential factors like changes in immune response mechanisms may play a role, indicating that careful treatment adjustments are necessary for children's health in CMD cases.
Introduction: The melting temperature (T) mapping method (TM) identifies bacterial species by intrinsic patterns of T values in the 16S ribosomal RNA gene (16S rDNA) extracted directly from whole blood. We examined potential clinical application of TM in children with bloodstream infection (BSI).
Methods: This was a prospective observational study at a children's hospital in Japan from 2018 to 2021.