Identification of chemical constituents and absorbed components in rat serum of (L.) Jacq. by UPLC-Q-exactive-MS.

(L.) Jacq. has anti-inflammatory, analgesic, haemostatic and antioxidant effects, but its pharmacological components are still unclear.

Two pathogen-inducible UDP-glycosyltransferases, UGT73C3 and UGT73C4, catalyze the glycosylation of pinoresinol to promote plant immunity in Arabidopsis.

UDP-glycosyltransferases (UGTs) constitute the largest glycosyltransferase family in the plant kingdom. They are responsible for transferring sugar moieties onto various small molecules to control many metabolic processes. However, their physiological significance in plants is largely unknown.

Preparation of pH-Responsive Tanshinone IIA-Loaded Calcium Alginate Nanoparticles and Their Anticancer Mechanisms.

Tanshinone IIA (Tan IIA) is a lipophilic active constituent derived from the rhizomes and roots of (Danshen), a common Chinese medicinal herb. However, clinical applications of Tan IIA are limited due to its poor solubility in water. : To overcome this limitation, we developed a calcium alginate hydrogel (CA) as a hydrophilic carrier for Tan IIA, which significantly improved its solubility.

Peptide Aptamer-Paclitaxel Conjugates for Tumor Targeted Therapy.

: Traditional paclitaxel therapy often results in significant side effects due to its non-specific targeting of cancer cells. Peptide aptamer-paclitaxel conjugates present a promising alternative by covalently attaching paclitaxel to a versatile peptide aptamer via a linker. Compared to antibody-paclitaxel conjugates, peptide aptamer-paclitaxel conjugates offer several advantages, including a smaller size, lower immunogenicity, improved tissue penetration, and easier engineering.

Numerical Simulation of Airflow Organization in Vulcanization Tanks for Waste Tires.

Currently, in the domestic practice of retreading tires using vulcanization tanks, some tanks exhibit uneven temperature distributions leading to low retreading success rates. To address that, this paper simulated the temperature and velocity fields during the heating process of vulcanization tanks for waste tire retreading. The results indicated that a higher heating power reduces the time required for the vulcanizing agent to reach the vulcanization condition, but it also increases the difference in tire temperature in the tank, with a severely uneven distribution of the temperature field.