Publications by authors named "Y Tomoyose"

Introduction: The study aimed to determine the efficacy and safety of biological disease-modifying antirheumatic drugs (bDMARDs) in the treatment of polymyalgia rheumatica (PMR) complicated by rheumatoid arthritis (RA).

Methods: Patients with PMR which could be classified as RA and who were treated with bDMARDs were included in the analysis. The primary endpoint was the clinical Polymyalgia Rheumatica Activity Score (Clin-PMR-AS) after 26 weeks of treatment, and the secondary endpoint was adverse events during the observation period.

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Article Synopsis
  • This study compared the effects of two diabetes medications: mitiglinide/voglibose and glimepiride, on blood sugar levels and blood vessel health in type 2 diabetes patients.
  • It was conducted as a multicenter, open-label, randomized crossover trial involving 30 hospitalized patients, measuring outcomes like blood glucose variability and vascular function over a 5-day treatment period for each drug.
  • Results showed that while both medications had similar effects on vascular function, mitiglinide/voglibose significantly reduced blood sugar fluctuations and time spent in extreme glucose ranges compared to glimepiride.
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