Publications by authors named "Y Tomiyama"

Earthquakes pose hazards to health care workers and patients in operating rooms. Proactive planning based on insights gained from past experiences is crucial for enhancing safety. Through a comprehensive literature review, we summarize challenges and lessons learned from real earthquake events to inform the development of effective safety measures in operating rooms.

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  • Type 2 diabetes mellitus (T2DM) significantly increases the risk of developing hepatocellular carcinoma (HCC), which is typically diagnosed late in diabetes patients due to insufficient surveillance criteria.
  • This study involved 330 T2DM patients with nonviral chronic liver disease diagnosed using imaging techniques, comparing clinical parameters between those with and without HCC.
  • Key risk factors for HCC included age over 65, alcohol consumption, and specific laboratory results, highlighting the need for adapted HCC surveillance strategies tailored to both younger and older T2DM patients.
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  • A 74-year-old man with severe aplastic anaemia achieved a long-term remission due to the growth of HLA allele-deficient clones, despite initial treatment complications.
  • After starting eltrombopag and ciclosporin, his blood counts eventually normalized over a span of 3 years, showing a complete recovery of blood cell production.
  • Research techniques like flow cytometry and deep sequencing indicated that his recovery relied on clones with mutations that interfered with antigen presentation, demonstrating a potential new approach for managing immune-related aplastic anaemia in similar patients.
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Immune thrombocytopenia (ITP) is characterized by early platelet destruction and impaired platelet production. Helicobacter pylori (H. pylori) infection seems to contribute to the pathogenesis in certain ITP patients in Japan.

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A woman in her sixties with portosystemic shunt and hepatic encephalopathy underwent open mesenteric vein ligation, resulting in improved portal flow and blood ammonia. In this case, 4D flow MRI was a valuable diagnostic and follow-up tool, visualizing and quantifying physiological portal hemodynamics with features distinct from those of contrast-enhanced CT and digital subtraction angiography. Our case study highlights the value of 4D flow MRI for managing portosystemic shunts.

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