Publications by authors named "Y Toba"
Introduction Monitored anesthesia care (MAC) is an anesthesia management method in which anesthesiologists use the minimum necessary intravenous anesthetics to achieve sedation and pain relief while maintaining spontaneous breathing. The challenge for the anesthesiologist is to find the correct balance between inhibiting the patient's stress response to invasive treatment, maintaining intraoperative hemodynamic stability, and doing so as quickly as possible. We hypothesized that diluting remifentanil (D-remi) to 10 μg/mL and increasing the rate of administration would increase the responsiveness of the syringe pump and allow for better control of anesthetic depth.
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- The central venous catheter (CVC) has been in use for over 50 years, originally for total parenteral nutrition, but its applications have expanded to areas like chemotherapy and intensive care, accompanying increased complications.
- Despite guidelines for safe CVC insertion, the risks associated with CVC removal have been overlooked, leading to potential complications such as air embolism, airway obstruction, and neurological issues.
- A case is presented where a CVC was improperly placed in the epidural space, resulting in arterial bleeding and neurological deterioration after its removal, necessitating emergency interventions.
Rationale: Chronic inflammatory demyelinating polyneuropathy (CIDP) is an autoimmune disorder that affects the peripheral nerves, leading to weakness and sensory symptoms. CIDP is a rare disease, and few studies have reported on anesthetic management in patients with this condition, especially the peripheral nerve block (PNB). Therefore, a safe and standardized anesthetic approach remains to be established.
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- Human milk is rich in carbohydrates, specifically human milk oligosaccharides (HMOs) and various types of glycans, but the specific profile of glycans had not been thoroughly studied until now.
- This study employed label-free chromatography-mass spectrometry (LC-MS) to analyze the variation in glycan composition and concentration in 200 samples of Japanese human milk from mothers 1-2 months postpartum.
- Findings showed that the presence of fucose linked to galactose affected the abundance of certain glycans and HMOs, with secretor mothers producing more of these compounds compared to nonsecretors, although the overall profile of glycans remained unchanged.
The bright red color of Parma ham is mainly derived from zinc protoporphyrin IX (ZnPP), which exists in both water-soluble and insoluble states. Water-soluble ZnPP mainly binds to hemoglobin, however, the presence of water-insoluble ZnPP remains unexplained. Therefore, we aimed to elucidate how ZnPP exists in a water-insoluble state by focusing on its binding substance.
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