Publications by authors named "Y Takihara"
Correlations between allergic transfusion reactions (ATRs) and allergic predisposition to food and inhaled allergens have been consistently reported. Food or pollen allergens circulating in the blood can be indirectly identified using the basophil activation test. In some cases, food or pollen allergens have been identified in transfused blood products that cause ATRs.
View Article and Find Full Text PDFBackground And Objectives: Quantifying the contribution of individual coagulation factors to haemostasis may aid our understanding of the haemostatic function in patients with rare coagulation deficiencies (RCDs) and the exploration of suitable treatments.
Materials And Methods: Reconstituted blood prepared from specific coagulation factor-deficient plasma (factor [F]II; prothrombin, FV, FVII, FVIII, FIX, FX, FXI or FXII) and red blood cell/platelet products were used to simulate the whole blood of patients with RCD. We prepared in vitro treatment models for patients with prothrombin deficiency using coagulation factor agents and fresh frozen plasma.
Article Synopsis
- - The T-TAS system, which analyzes how platelets contribute to blood clotting, struggles with low platelet counts, prompting the introduction of a haemodilution chip designed for such conditions.
- - Blood samples were created using red blood cell products and platelet products, specifically tested for platelet counts of 50 × 10/μL, and various aggregation tests were conducted with different inducers like ADP.
- - The study found that the new HD chip reliably assessed haemostatic functions at low platelet counts, showing significant correlations with certain aggregation measures and suggests potential for future in vivo testing.
Article Synopsis
- Research shows that stem cell therapy relies on their ability to grow and differentiate, but the exact mechanisms behind their healing effects are unclear.
- A study discovered that umbilical cord blood cells, even after being damaged by X-irradiation, can still promote recovery in a mouse stroke model by rapidly transferring small metabolites to help repair tissue.
- These findings suggest that instead of relying solely on the growth of stem cells, the therapeutic benefits might come from stimulating new blood vessel and neuron formation through the metabolites released by X-irradiated cells.
Prcis: Large amount of trabeculotomy with Kahook Dual Blade (KDB) confers better intraocular pressure (IOP) lowering.
Purpose: We compared the postoperative outcomes of trabeculotomy using the KDB in patients with exfoliation glaucoma (EXG) and primary open angle glaucoma between the 120-degree incision and the 210- to 240-degree incision groups.
Patients And Methods: We retrospectively analyzed the postoperative outcomes of trabeculotomy performed using the KDB in 101 eyes with EXG and primary open angle glaucoma, who received 120- and 210- to 240-degree incisions at Kumamoto University Hospital between April 25, 2018, and August 11, 2021.