Publications by authors named "Y Sudo"
Introduction: Compared to platinum-based therapies, a combination of ipilimumab (anti-CTLA-4) and nivolumab (anti-PD-1) has demonstrated improved outcomes in advanced non-small cell lung cancer (NSCLC), albeit with higher rates of immune-related adverse events (irAEs). This multicenter retrospective study evaluated the efficacy and safety of nivolumab and ipilimumab with or without chemotherapy (NI and NICT) in real-world clinical settings.
Methods: We enrolled 215 treatment-naïve NSCLC patients who received NI or NICT between December 2020 and May 2023 at 14 institutions in Japan.
Development of efficient electrocatalysts for hydrogen evolution reactions (HERs) is necessary to achieve environmentally friendly and sustainable hydrogen production. To reduce cost and to circumvent the scarcity of platinum, the most efficient catalyst for HER, it is essential to develop catalysts using ubiquitous base metals or minimal amounts of precious metals. Bis(diimino)metal (MDI) coordination nanosheets are potential HER catalysts because their electric conductivities, two-dimensionality, and porous structures provide large surface areas and efficient mass and electron transfer.
View Article and Find Full Text PDFBackground: The histological improvement in liver fibrosis in patients with hepatitis C who achieved a sustained virological response (SVR) to direct-acting antiviral (DAA) treatment has not been comprehensively investigated. Therefore, we assessed the histological changes in liver fibrosis among patients with hepatitis C who underwent long-term follow-up after achieving SVR to treatment with DAA.
Methods: This retrospective study enrolled 71 patients with hepatitis C who achieved SVR to treatment with DAA.
Article Synopsis
- Proximal renal tubular dysfunction is common during diabetic ketoacidosis (DKA) in newly diagnosed type 1 diabetes, but previous studies have lacked comprehensive analysis of its multiple functions and have not explored distal tubular function.
- In a study involving patients with and without DKA, those with DKA showed significantly higher levels of urinary β2-microglobulin and lower blood pH and phosphorus reabsorption, indicating renal dysfunction.
- The findings suggest that DKA in type 1 diabetes may lead to multiple proximal tubular dysfunctions resembling transient Fanconi syndrome, while distal renal tubular acidosis is unlikely to be present.
Objective: To investigate the recovery processes of pusher behavior (PB) and unilateral spatial neglect (USN) based on the severity of PB and USN, and to determine the relationship between activities of daily living (ADL) independence levels.
Design: This retrospective study aimed to examine the temporal changes and their association with ADL independence levels based on the severity of PB and USN.
Setting: Recovery ward of Moriyama Neurological Center Hospital between March 2017 and October 2022.