Publications by authors named "Y Sih Ibet Marie"
Background: Glioblastoma (GBM) is the most common devastating primary brain cancer in adults. In our clinical practice, median overall survival (mOS) of GBM patients seems increasing over time.
Methods: To address this observation, we have retrospectively analyzed the prognosis of 722 newly diagnosed GBM patients, aged below 70, in good clinical conditions (i.
New class of RNA biomarker for endometriosis diagnosis: The potential of salivary piRNA expression.
Eur J Obstet Gynecol Reprod Biol
December 2023
Article Synopsis
- This study investigated the expression of piwiRNA (piRNA) in patients with endometriosis, aiming to develop a saliva-based diagnostic tool for the condition.
- Using saliva samples from 200 patients, 201 piRNAs were identified, but none showed strong predictive value (AUC ≥ 0.70) for diagnosing endometriosis, with only three piRNAs having moderate diagnostic potential.
- The research also indicated correlations between specific piRNAs and patient age and hormonal treatment, suggesting piRNA analysis could be a valuable addition to clinical evaluations of endometriosis.
Aims: The distinction between CNS WHO grade 2 and grade 3 is instrumental in choosing between observational follow-up and adjuvant treatment for resected astrocytomas IDH-mutant. However, the criteria of CNS WHO grade 2 vs 3 have not been updated since the pre-IDH era.
Methods: Maximal mitotic activity in consecutive high-power fields corresponding to 3 mm was examined for 118 lower-grade astrocytomas IDH-mutant.
Correction: Association of Rare Genetic Variants in Opioid Receptors with Tourette Syndrome.
Tremor Other Hyperkinet Mov (N Y)
July 2023
Article Synopsis
- The article mentioned has been corrected to address previous errors identified in its content.
- The correction enhances the accuracy of the information for readers and researchers relying on the data.
- The DOI provided (10.5334/tohm.464) allows access to the updated and accurate version of the article.
Article Synopsis
- The study investigates the connection between Lynch syndrome (LS) and gliomas, focusing on the prevalence of mismatch repair deficiency (MMRd) in a large sample of unselected gliomas to inform treatment and prevention strategies.
- Researchers analyzed 1,225 treatment-naive adult gliomas from 2017 to June 2022, finding that 0.73% were MMRd and 0.41% had LS, with most cases diagnosed in individuals under 50.
- The findings emphasize the importance of systematic screening for MMRd and LS in glioblastomas, particularly in patients diagnosed before turning 50 years old.