Publications by authors named "Y Shiraki"
Article Synopsis
- Brown adipose tissue (BAT) is critical for energy consumption, and its dysfunction can lead to metabolic diseases and obesity, especially as we age.
- The study identifies that perineurial cells, which have reduced antioxidant capacity due to lacking superoxide dismutase 2, impair BAT function by causing sympathetic nerve denervation and reducing fat oxidation.
- Targeting Meflin-expressing stromal cells may be a promising strategy to strengthen BAT function and combat age-related metabolic issues.
Ixodid ticks are significant vectors of pathogens affecting both humans and animals. Biological control with natural enemies represents a sustainable tool for managing ticks. However, there is a substantial lack of knowledge about the natural enemies of ticks.
View Article and Find Full Text PDFYezo virus (YEZV) is an emerging tick-borne virus that causes acute febrile illness. It has been continuously reported in patients and ticks in Japan and China since its first identification in Hokkaido, Japan. While serological tests have demonstrated that YEZV infections are prevalent in wild animals, such as raccoons (Procyon lotor), the determinants of infection in wild animals remain largely unknown.
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- - The case discusses a rare instance of pulmonary metastasis from renal angiomyolipoma (AML) in an 82-year-old woman, highlighting the need to differentiate between multicentric growth and true metastasis.
- - This patient had pulmonary nodules that were uniquely composed of fat, and her condition remained benign over a decade, emphasizing the atypical behavior of AML.
- - Whole-exome sequencing revealed specific mutations in the lung lesions, including a TSC2 mutation not found in her blood, suggesting that these lesions originated from her renal AML, which underscores the importance of recognizing such presentations for better diagnosis and treatment.
Revealing interactions between ticks and wild animals is vital for gaining insights into the dynamics of tick-borne pathogens in the natural environment. We aimed to elucidate the factors that determine tick infestation in wild animals by investigating ticks on invasive raccoons (Procyon lotor) in Hokkaido, Japan. We first examined the composition, intensity, and seasonal variation of ticks infesting raccoons in six study areas in Hokkaido from March 2022 to August 2023.
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