Publications by authors named "Y Shiobara"

Article Synopsis
  • * Research showed that Pro-Hyp treatment led to smaller fat cells and increased expression of genes important for brown fat function, without affecting PPARγ levels, while also boosting mitochondrial activity, indicating improved cell functionality.
  • * The findings suggest that Pro-Hyp promotes brown adipocyte differentiation, highlighting its potential as a treatment for obesity, but more research is necessary to confirm these effects and explore its impact on other types of fat cells.
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Aims: We aimed to assess the difficulty in taking solid oral dosage forms (SODFs) among older people with dysphagia and clarify the relationship between difficulty in swallowing SODFs and swallowing function.

Methods And Results: Outpatients from a dysphagia clinic aged ≥65 years were asked yes-or-no questions about the applicability of eight items regarding difficulty in taking SODFs. Additionally, a videofluorographic swallowing study (VFSS) was performed to assess their swallowing function.

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The genetic and molecular basis of flagellar motility has been investigated for several decades, with innovative research strategies propelling advances at a steady pace. Furthermore, as the phenomenon is examined in diverse bacteria, new taxon-specific regulatory and structural features are being elucidated. Motility is also a straightforward bacterial phenotype that can allow undergraduate researchers to explore the palette of molecular genetic tools available to microbiologists.

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Article Synopsis
  • The freshwater planarian is a key model organism for studying tissue regeneration, with genomic research identifying important genes involved in the regeneration process.
  • In a study, researchers found that knocking down the Smed-dlp1 gene, which is crucial for synthesizing Coenzyme Q (CoQ), resulted in lower levels of CoQ9 and rhodoquinone 9, leading to decreased cell turnover and impaired regeneration in planarians.
  • Interestingly, supplementing the diet with α-tocopherol partially mitigated negative effects, indicating that oxidative stress from reduced CoQ levels plays a significant role in planarian regeneration and overall tissue health.
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We recently experienced one each of 2 types of recurrent respiratory papillomatosis (RRP). Case 1 (juvenile-onset type): A 30-year-old woman presenting with bloody sputum and large tumors with cavities on her chest Xray film, was referred to our hospital. She had been diagnosed with laryngeal papillomatosis when she was three years old.

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