Publications by authors named "Y Shiba"
Article Synopsis
- The study explores how membrane stiffness affects cell behavior and examines the physical properties of membranes in a lab setting.
- Researchers introduced magnetic nanoparticles into breast cancer cells and used magnetic fields to see if they could damage the endosomal membrane.
- Findings show that applying a strong static magnetic field can induce membrane damage in early endosomes, particularly when using a magnetic field strength of 100 mT for five minutes, highlighting the potential for controlled damage with magnetic fields.
Purpose: This cross-sectional study aimed to clarify the relationship between dysphagia and social isolation among community-dwelling older people.
Methods: The study participants were 238 community-dwelling older people (168 women; mean age, 74.0 ± 5.
Article Synopsis
- Mutations in the IDH gene are crucial for the development of astrocytoma and oligodendroglioma, but their role in tumor maintenance and aggressive transformation is still unclear.
- Researchers observed an unusual case of IDH-mutant astrocytoma that transformed into two distinct types: one with IDH mutations and another without, showing differing characteristics in aggression.
- The IDH-wild-type component lacked the IDH mutation due to chromosome loss, and also acquired additional genetic changes, indicating that these tumors may become independent of IDH mutations and develop resistance to treatments targeting those mutations.
Background And Purpose: Mild cognitive impairment (MCI) is a predictor of future age-related dementia. We herein investigated associations of MCI with higher-level functional capacities, as well as with subjective difficulty regarding these functions, in community-dwelling older people, to identify a simple method for early MCI detection.
Method: We administered a test battery to 118 community-dwelling older people living in an urban area.
Owing to increasing super-aging societies, older adults will be encouraged to continue working. Although demand exists for older adults to continue working in Japanese society, the enabling factors have not been clarified. This study aimed to clarify (1) the life functions that affect the working status among younger-older adults who continue to work and those who do not via the Kihon Checklist (KCL) and (2) examine whether the number of areas of difficulties in daily functions of the KCL affected older adults' employment status.
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