Publications by authors named "Y Sharifi"
Medical and surgical treatments for cystic echinococcosis (CE) are challenged by various complications. This study evaluates in vitro protoscolicidal activity of piperine-loaded mesoporous silica nanoparticles (PIP-MSNs) against protoscoleces of Echinococcus granulosus. MSNs were prepared by adding tetraethyl orthosilicate to cetyltrimethylammonium bromide and NaOH, and then loaded with PIP.
View Article and Find Full Text PDFPurpose: The thyroid imaging reporting and data system (TIRADS) was developed as a standard global term to describe thyroid nodule risk features, aiming to address issues such as variability and low reproducibility in nodule feature detection and interpretation by different physicians. The objective of this study is to comprehensively study articles that utilize AI techniques to design and develop decision support systems for classifying thyroid nodule risk on the basis of various TIRADS guidelines from ultrasound images.
Methods: This protocol includes five steps: identification of key research questions of the review, descriptions of the systematic literature search strategies, criteria for study inclusion and exclusion, study quality measures, and the data extraction process.
Article Synopsis
- Persistent high blood sugar levels significantly increase the risk of cognitive disorders in older adults with diabetes, as both type 1 and type 2 diabetes are linked to cognitive impairment.
- A study involving 1,533 older adults showed that 45.2% experienced cognitive impairment, with higher average hemoglobin A1C and blood glucose levels in those affected.
- Analysis revealed that diabetes was associated with a 48% higher likelihood of cognitive impairment, particularly in older individuals, women, and those with other health issues like high blood pressure.
Article Synopsis
- Frailty is a complex condition in older adults that makes them more vulnerable to stress, and metabolomics studies can help us understand its underlying mechanisms.
- A systematic review analyzed 21 studies that evaluated the metabolomics profile of frail individuals, highlighting significant differences in metabolite levels compared to healthier subjects.
- Key findings included lower levels of branched-chain amino acids and carnitine, along with higher levels of glutamate and glutamine in frail individuals, indicating a complex biochemical relationship that could help expand our understanding of frailty.
Cystic echinococcosis (CE), is one of the common parasitic infections of domestic animals and humans caused by the larval stages of the tapeworm . This research aimed to identify of CE cysts in cattle isolates from Shiraz slaughterhouse using molecular technique. Thirty CE cysts isolates were collected and total DNA was extracted from protoscolices or the germinal layer of each cyst followed by polymerase chain reaction (PCR) using cytochrome c oxidase I (cox1) and NADH dehydrogenase subunit 1 (NADH-1) mitochondrial genes (~ 450 bp) and sequencing.
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