Publications by authors named "Y Sha"
Long noncoding RNA (lncRNA) PTTG3P has been demonstrated to participate in the development of hepatocellular carcinoma (HCC) by targeting the mRNA PTTG1. The present study aimed to investigate the diagnostic efficacy of serum lncRNA PTTG3P, mRNA PTTG1 and their combination for the diagnosis and prognosis of HCC. A total of 373 participants were enrolled in the present study, including 73 patients with HCC, 100 patients with chronic hepatitis B (CHB), 100 patients with liver cirrhosis (LC) and 100 healthy controls (HCs).
View Article and Find Full Text PDFCervical lesions pose a significant threat to women's health worldwide. Colposcopy is essential for screening and treating cervical lesions, but its effectiveness depends on the doctor's experience. Artificial intelligence-based solutions via colposcopy images have shown great potential in cervical lesions screening.
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- Ethanol-tolerant Saccharomyces cerevisiae is essential for efficient ethanol production in starch-based biorefineries, especially during high-gravity fermentation.
- The study involved using adaptive evolution with higher initial ethanol concentrations to develop a strain that showed enhanced tolerance, which improved glucose consumption and ethanol output significantly under various solid loadings of corn and cassava.
- Genome re-sequencing revealed 504 mutations linked to increased tolerance, particularly highlighting the PAM1 gene's role, paving the way for better metabolic engineering strategies in ethanol production.
Article Synopsis
- The study simulated the effects of both toxic and non-toxic substances on aquatic organisms, measuring various parameters related to their biomass and colony formation.
- Toxic and non-toxic substances inhibited the colony formation of certain organisms and affected soluble polysaccharide and protein content, particularly when coexisting with specific species.
- The research highlighted the dominance of Proteobacteria in different treatment groups, with a noted increase in bacteria that degrade organic pollutants in the toxic treatment, contributing to an understanding of aquatic ecosystems under eutrophic conditions.