Publications by authors named "Y Sawai"

Background And Aims: Perforation is a rare but serious adverse event associated with endoscopic retrograde cholangiopancreatography (ERCP). There is no consensus to guide clinicians in the management of ERCP-related duodenal perforations, making it difficult to determine whether surgical or endoscopic treatment is optimal. The present study retrospectively evaluated the characteristics and clinical outcomes of patients who experienced ERCP-related duodenal perforations according to the mechanism of injury.

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: Restoration of the mandibular region after segmental resection surgery is crucial for masticatory function and facial aesthetics. The precision of three-dimensional printers has advanced in recent years, enabling the development of fully customized reconstruction plates. In recent years, three-dimensional printing technology has been applied in the field of dental and oral surgery.

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Background: Asthma is a widespread chronic respiratory disease that poses a significant public health challenge. The current study investigated the associations between air pollution and asthma severity among individuals residing near the Sohar industrial port (SIP) in Oman. Despite the presence of multiple major industrial complexes in Oman, limited knowledge regarding their impact on respiratory health is accredited.

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Article Synopsis
  • Protein lactylation, a modification linked to glycolysis, plays a role in gene regulation, but its significance in cancer, especially pancreatic tumors, is still under investigation.
  • The study found increased lactylation in the nuclei of various pancreatic tumors alongside elevated levels of hypoxia-inducible factor-1α, suggesting a connection with tumor hypoxia.
  • Additionally, the chemotherapy drug gemcitabine was shown to decrease histone lactylation, indicating that protein lactylation might be a factor in pancreatic cancer development and treatment.
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