FOXO1 pathway activation by VISTA immune checkpoint restrains pulmonary ILC2 functions.

Type-2 innate lymphoid cells (ILC2s) play a pivotal role in the development of airway hyperreactivity (AHR). However, the regulatory mechanisms governing ILC2 function remain inadequately explored. This study uncovers V-domain Ig suppressor of T cell activation (VISTA) as an inhibitory immune checkpoint crucial for modulating ILC2-driven lung inflammation.

Finding the Right Hepatic Artery Branching from the Gastroduodenal Artery in a Patient Undergoing Gastrectomy: A Rare Case of an Anatomical Variant.

Numerous vascular anomalies of the hepatic artery have been reported. Protection of the hepatic arterial supply is important during gastrectomy. We herein report a case in which an anatomical variant of the hepatic artery was discovered in a patient undergoing laparoscopic distal gastrectomy with D1+ lymph node dissection for early gastric cancer.

Impact of Lymphocyte/Monocyte Ratio on Outcomes in Patients with Remnant Gastric Cancer After Gastrectomy.

Background: The inflammatory response plays a crucial role in tumor development. Inflammatory markers are recognized prognostic factors in many types of cancer, including gastric cancer. However, the correlation between inflammatory markers and prognosis in remnant gastric cancer (RGC) remains unclear.

A Case of Allergic Bronchopulmonary Mycosis Caused by Cordyceps farinosa, a Species of Caterpillar Fungi.

A female patient in her thirties presented with persistent cough and sputum, unresponsive to conventional treatments. Chest imaging showed infiltrative opacities and high attenuation mucus. On laboratory examination, eosinophil counts and immunoglobulin E were elevated.