Publications by authors named "Y Sakabe"
Although esophageal stenting is one treatment option as a palliative treatment for tracheoesophageal fistulas, serious complications are associated with stent migration. Some reports have described stent fixation using various devices to prevent stent migration. However, these have yet to be sufficiently examined.
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- Nectin-4, a cell adhesion molecule, is found to be overexpressed in various cancers and may serve as both a disease marker and therapeutic target.
- In a study, maternal serum levels of Nectin-4 were significantly higher in women with pre-eclampsia compared to those with normal pregnancies, while no increase was seen in cases of unexplained fetal growth retardation.
- The findings suggest that Nectin-4 could be a promising new biomarker for diagnosing and predicting severe pre-eclampsia.
Multilocular cystic leiomyomas rarely develop following myomectomy. To the best of our knowledge, there are no published reports on recurrent multilocular cystic leiomyoma following myomectomy. We here present such a case.
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- Researchers wanted to find out if a virus called cytomegalovirus (HCMV) is linked to a problem called fetal growth restriction (FGR) where babies don't grow as they should.
- They studied 78 cases of FGR and looked at tissue samples from the placentas, finding that about 6.8% of the samples showed signs of HCMV.
- The study concluded that while they found HCMV in some placentas, it didn't seem to cause any noticeable differences in health between the affected mothers and babies compared to others with FGR.
Article Synopsis
- A specific gene was found to be significantly overexpressed in pre-eclamptic placentas, suggesting its potential role in the disease's development.
- Researchers used RNA sequencing to analyze placental expression in women with pre-eclampsia versus those with healthy pregnancies, discovering a linked long non-coding RNA (lncRNA) gene nearby the overexpressed gene.
- While the lncRNA's expression did not influence the overexpressed gene's levels, its transcript was related to birth and placental weights, indicating it may play a crucial role in the mechanisms of pre-eclampsia.