Publications by authors named "Y S Hedberg"
Introduction: Traces of hexavalent chromium, Cr(VI), are a major concern for skin contact with Cr-tanned leather. Current extraction methods (ISO 17075-1:2017) for Cr(VI) testing do not necessarily reflect the true potential of surface-formed Cr(VI), as extracted concentrations are dependent on previous storage and atmospheric conditions.
Objectives: To test whether a spiking method protocol can distinguish leathers with high and low risks of releasing Cr(VI).
The interaction of human proteins and metal species, both ions and nanoparticles, is poorly understood despite their growing importance. These materials are the by-products of corrosion processes and are of relevance for food and drug manufacturing, nanomedicine, and biomedical implant corrosion. Here, we study the interaction of Cr(III) ions and chromium oxide nanoparticles with bovine serum albumin in physiological conditions.
View Article and Find Full Text PDFIntroduction: Leather has been a significant source of chromium (Cr) allergy in Denmark since the 1990s. More recently, cobalt (Co) allergy has been identified in leather as a source of allergic contact dermatitis.
Objectives: To measure Cr and Co levels in Danish leather goods.
Article Synopsis
- - Researchers studied how different protein compounds and manufacturing methods affect the corrosion and wear of cobalt-chromium-molybdenum (CoCrMo) alloys, commonly used in biomedical applications, using techniques like electrochemistry and microscopy.
- - The experiment involved testing the alloys in a specific pH environment with added bovine serum albumin (BSA) and fibrinogen (Fbn) to see their effects on metal release and corrosion, finding that the proteins increased metal release and improved lubrication, reducing wear severity.
- - Results showed that the wear areas of the alloys were more oxidized than surrounding areas, and significant changes in the oxidation of molybdenum were noted when proteins were absent, indicating the proteins’
Serum Albumin Aggregation Facilitated by Cobalt and Chromium Metal Ions.
ACS Appl Bio Mater
September 2023
Article Synopsis
- The study investigates how cobalt (Co) and chromium (Cr) ions affect the aggregation of bovine serum albumin (BSA), a key serum protein, which could impact the corrosion of biomedical CoCr alloys and health.
- Using various methods, the researchers found that both metal ions could induce BSA aggregation, with Co(II) reducing its stability more than Cr(III).
- The proposed mechanism for this aggregation involves salt bridging between BSA protein molecules, with metal ions preferentially binding to the proteins and depleting them from the surrounding solution.