Publications by authors named "Y S H S Chakravarthy"

Background: Advances in oral and periodontal disease diagnostic research are moving towards methods wherein periodontal risk can be identified and quantified by objective measures such as bio-markers. Given the roles of vitamin D binding protein (DBP) in modulating the immune response and in the transport of vitamin D, it is hypothesised that quantitative changes of vitamin DBP are associated with periodontal disease.

Aim: The aim of the current study is to measure DBP levels in serum and gingival crevicular fluid (GCF) of patients with generalised chronic periodontitis, in comparison to healthy controls.

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Article Synopsis
  • The study focuses on regenerative endodontic techniques, specifically assessing the effectiveness of 0.2% chitosan and papain as alternatives to 17% EDTA for promoting fibrin formation in root canals with open apices.
  • Twenty-five freshly extracted human mandibular premolars were used in the experiment, which involved comparing the fibrin density after different irrigation treatments.
  • Findings indicated that the combination of EDTA-NSS and papain resulted in higher fibrin density compared to the use of chitosan, showing positive results for all irrigants tested in revitalizing dental pulp tissue.
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Models of pathogenesis help in integrating the data available from current scientific research, which aid in comprehensive understanding of the disease. This stereotypic representation of a disease in the form of a conceptual model helps in translation of new information into practical applications. The evolution in the knowledge of pathogenesis of periodontal disease can lead to a revolution in treatment modalities.

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Revascularization of the dental pulp is an emerging regenerative endodontic approach in which a new tissue is formed inside the root canal by induction of blood clot, allowing the continuation in the development of root. In this case report, the effective management of previously fractured immature tooth with the presence of foreign body (wire) inside the canal and radiographic periapical radiolucency had been described. A 17-year-old patient with immature fractured upper left lateral incisor with radiographic evidence of foreign body (wire) inside the canal was treated with removal of wire by H file followed by revascularization protocol that used working length determination, 5.

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Aims: This study was a single-arm trial to obtain preliminary data on the efficacy of collagen membranes impregnated with recombinant human fibroblast growth factor-2 (rhFGF-2) in the treatment of Miller's Class I and II gingival recessions.

Materials And Methods: Twenty-one individuals (34 sites) presenting with localized Miller's Class I and II gingival recessions were included in this study. Following a standard surgical protocol, rhFGF-2-impregnated membranes were placed in sites with gingival recession.

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