A Biomimetic Sweeping Microrobot for Active Therapy of Ulcerative Colitis.

Overproduction of pathogenic cell-free DNA (cfDNA) and reactive oxygen species (ROS) plays crucial roles in the onset and perpetuation of ulcerative colitis (UC). Inspired by sweeping robots, a magnesium@polylactic acid-glycolic acid copolymer@polyethylenimine (Mg@PLGA@PEI) microswimmer capable of cleaning off deleterious disease triggers along its path of progress is designed. Mg@PLGA@PEI is successfully synthesized by adopting a core-shell structure with a small opening which allows for Mg-water reaction.

The Relationship between Self-objectification and Adolescent Appearance Anxiety: A Mediated Model with Moderation.

Background: The physical appearances of an individual are frequently scrutinized and evaluated by others in daily life. The rise of social media has intensified this scrutiny, leading to increased attention to and comparison of the appearance of an individual with others, leading to psychological challenges such as appearance anxiety. This study, from the perspective of self-objectification, explored the influence of self-objectification on appearance anxiety and the role of social appearance comparison and self-compassion in the relationship between self-objectification and appearance anxiety.

A new method for identifying and evaluating depressive disorders in young people based on cognitive neurocomputing: an exploratory study.

Background: Depressive disorders are one of the most common mental disorders among young people. However, there is still a lack of objective means to identify and evaluate young people with depressive disorders quickly. Cognitive impairment is one of the core characteristics of depressive disorders, which is of great value in the identification and evaluation of young people with depressive disorders.

Bacterial motility depends on a critical flagellum length and energy-optimized assembly.

The flagellum is the most complex macromolecular structure known in bacteria and is composed of around two dozen distinct proteins. The main building block of the long, external flagellar filament, flagellin, is secreted through the flagellar type-III secretion system at a remarkable rate of several tens of thousands of amino acids per second, significantly surpassing the rates achieved by other pore-based protein secretion systems. The evolutionary implications and potential benefits of this high secretion rate for flagellum assembly and function, however, have remained elusive.

Tunable superconductivity coexisting with the anomalous Hall effect in a transition metal dichalcogenide.

Transition metal dichalcogenides display a high technological potential due to their wide range of electronic ground states. Here, we unveil that by tuning hydrostatic pressure P, a cascade of electronic phase transitions can be induced in the few-layer transition metal dichalcogenide 1T'-WS. As P increases, we observe the suppression of superconductivity with the concomitant emergence of an anomalous Hall effect (AHE) at GPa.