Epidemiological Features of Sinonasal Adenocarcinoma and Prognostic Nomogram: A Study Based on the SEER Database.

Objective: Our study aimed to update demographic profiles of sinonasal adenocarcinoma (SNAC) between 2000 and 2020, identify independent prognostic risk factors, and devise a predictive nomogram for overall survival (OS).

Methods: Utilizing the Surveillance, Epidemiology, and End Results (SEER) database, cases of SNAC from 2000 to 2020 were analyzed for incidence trends. Univariate and multivariate Cox regression models helped pinpoint factors impacting patient survival.

Laboratory-simulated marine heatwave enhances physiological damage to mussels exposed to titanium dioxide nanoparticles by disrupting the gut-hepatopancreas axis.

The aggregation state of nano-TiO in the environment is altered under marine heatwaves (MHWs), thus affecting its bioavailability and toxicity to the marine organisms. Here, we investigated the toxic mechanisms and effects of nano-TiO on gut-hepatopancreas axis health of Mytilus coruscus exposed to 25 and 250 μg/L of nano-TiO under laboratory-simulated MHW. Compared with the control conditions or post-MHW cooling phase, prolonged MHW exposure significantly inhibited digestive function, decreased immune-related enzymes activities, and caused neurotoxicity in the mussels.

R(3780) Resonance Interpreted as the 1^{3}D_{1}-Wave Dominant State of Charmonium from Precise Measurements of the Cross Section of e^{+}e^{-}→Hadrons.

We report the precise measurements of the cross section of e^{+}e^{-}→hadrons at center-of-mass energies from 3.645 to 3.871 GeV.

Global, regional, and national burden of primary liver cancer attributable to metabolic risks: an analysis of the Global Burden of Disease Study 1990-2021.

Background: The global burden of metabolic diseases is increasing, but estimates of their impact on primary liver cancer are uncertain. We aimed to assess the global burden of primary liver cancer attributable to metabolic risk factors, including high body mass index (BMI) and high fasting plasma glucose (FPG) levels, between 1990 and 2021.

Methods: The total number and age-standardized rates of deaths and disability-adjusted life years (DALYs) from primary liver cancer attributable to each metabolic risk factor were extracted from the Global Burden of Disease Study 1990-2021.