MacNet: a mobile attention classification network combining convolutional neural network and transformer for the differentiation of cervical cancer.

Background: Cervical cancer remains a critical global health issue, responsible for over 600,000 new cases and 300,000 deaths annually. Pathological imaging of cervical cancer is a crucial diagnostic tool. However, distinguishing specific areas of cellular differentiation remains challenging because of the lack of clear boundaries between cells at various stages of differentiation.

External validation of multiparametric magnetic resonance imaging-based decision rules for characterizing breast lesions and comparison to Kaiser score and breast imaging reporting and data system (BI-RADS) category.

Background: Breast imaging reporting and data system (BI-RADS) provides standard descriptors but not detailed decision rules for characterizing breast lesions. Diffusion-weighted imaging (DWI) and T2-weighted imaging (T2WI) are also not incorporated in the BI-RADS. Several multiparametric magnetic resonance imaging (mpMRI)-based decision rules have been developed to differentiate breast lesions, but lack external validation.

Pyrimidine-based dual-target inhibitors targeting epidermal growth factor receptor for overcoming drug resistance in cancer therapy(2006-present).

The epidermal growth factor receptor (EGFR) is a pivotal member of the epidermal growth factor receptor family, exerting crucial regulatory influence on cellular physiological processes, particularly in relation to cell growth, proliferation, and differentiation. In recent years, numerous EGFR inhibitors have been introduced to the market; unfortunately, the effectiveness of single-target EGFR inhibitors has been compromised due to the development of drug resistance caused by EGFR mutations. Despite attempts by some researchers to address this issue through combination therapy with two or more drugs, instances of dose-limiting toxicities have been observed.

Effect of photobiological regulation of green laser on orthodontic tooth retention in rats.

Green lasers have a stronger effect on promoting osteoblast differentiation, which is critical for orthodontic tooth retention. This study investigated the impact of green laser photobiomodulation on orthodontic tooth retention in rats. A total of 100 male Sprague-Dawley rats were divided into two groups: Group A (control) and Group B (green laser irradiation).

Cardiac papillary fibroelastoma involving the mitral valve: A case report.

Rationale: Cardiac papillary fibroelastoma (CPF) is a rare cardiac tumor that can lead to severe and potentially fatal complications such as stroke, myocardial infarction, and sudden cardiac death. The rarity of CPF makes it challenging for clinicians to diagnose and treat, highlighting the importance of timely and accurate diagnosis to prevent catastrophic outcomes. This case report aims to contribute to the clinical understanding of CPF involving the mitral valve (MV), providing insights into diagnosis and treatment strategies.