Anti-neuropathic Pain Mechanistic Study on Essential Oil, Precocene II, Caryophyllene, or Longifolene as Single Agents and in Combination with Pregabalin.

Background: Neuropathic pain has become a contributor to the global burden of illness. However, the currently available drugs exhibit inadequate pain relief and significant side effects. Our previous study demonstrated that the essential oil of Ageratum conyzoides exerts potent antineuropathic pain activity through opioid receptor activation.

Wound Healing Effectivity of the Ethanolic Extracts of L. Leaf (White and Purple Flower Type) and and Gel Preparation in Animal Model.

Unlabelled: The study's objective was to determine the wound healing activity of the combination of ethanolic extracts of L. leaf (white and purple), , and astaxanthin gel preparation.

Materials And Methods: For in-gel preparation, three different formulas of gelling agents, namely carbopol 934 (1%), hydroxypropyl methylcellulose (HPMC) (9%), and natirum-carboxymethylcellulose (Na-CMC) (4%), were employed.

Anti-Neuropathic Pain Activity of Ageratum conyzoides L due to the Essential Oil Components.

Background: Neuropathic pain is one of the contributors to the global burdens of illness. At present many patients do not achieve satisfactory pain relief even with synthetic painkillers. Taking this into consideration, it is necessary to search for natural product-derived alternative treatment with confirmed safety and efficacy.

Comparison and Impact of The Short-Term Use of Some Non-Aspirin NSAIDs on Bleeding Time of Mice.

Background: Non-Steroidal Anti Inflammation Drugs (NSAIDs) have shown effectivity in pain relief and are the most prescribed around the world. However, NSAIDs impair hematological aspects that may lead to the life-threatening events.

Objective: The objective of the study is to determine the comparison and impact of the short-term use of some non-aspirin NSAIDs on bleeding time.