Evaluation of autoimmune phenomena in patients with nonalcoholic fatty liver disease on the basis of liver pathology.

Background: Autoimmune phenomena can be used in some patients with nonalcoholic fatty liver disease (NAFLD) in the clinic, but these patients are not autoimmune hepatitis patients.

Aim: To determine whether autoimmunity is present in patients with NAFLD, this study was performed.

Methods: A total of 104 patients with NAFLD diagnosed by liver biopsy at Tianjin Second People's Hospital between 2019 and 2023 were enrolled.

Calcineurin: An essential regulator of sleep revealed by biochemical, chemical biological, and genetic approaches.

Research into mechanisms underlying sleep traditionally relies on electrophysiology and genetics. Because sleep can only be measured on whole animals by behavioral observations and physical means, no sleep research was initiated by biochemical and chemical biological approaches. We used phosphorylation sites of kinases important for sleep as targets for biochemical and chemical biological approaches.

Effects of ADHD and ADHD medications on depression and anxiety in children and adolescents: A systematic review and meta-analysis.

This systematic review and meta-analysis aimed to comprehensively assess the effects of attention-deficit/hyperactivity disorder (ADHD) and ADHD medications on the risk of depression and anxiety in children and adolescents. A comprehensive search of PubMed, Embase, Cochrane Library, and Web of Science was conducted up to January 30, 2024. The outcomes were depression and anxiety.

A new approach for bin packing problem using knowledge reuse and improved heuristic.

The two-dimensional (2D) irregular packing problem is a combinatorial optimization problem with NP-complete characteristics, which is common in the production process of clothing, ships, and plate metals. The classic packing solution is a hybrid algorithm based on heuristic positioning and meta-heuristic sequencing, which has the problems of complex solving rules and high time cost. In this study, the similarity measurement method based on the twin neural network model is used to evaluate the similarity of pieces in the source task and the target task.

Numerical simulation study on the influence of bend diameter rate on the flow characteristics of nature gas hydrate particles.

Bend pipe is a common part of long distance pipeline. There is very important to study the flow law of hydrate particles in the bend pipe, and pipeline design will be optimized. In addition, the efficiency and safety of pipeline gas transmission will be improved.