Publications by authors named "Y Polfrit"
Background And Objectives: Pediatric encephalitis has a wide range of etiologies, clinical presentations, and outcomes. This study seeks to classify and characterize infectious, immune-mediated/autoantibody-associated and unknown forms of encephalitis, including relative frequencies, clinical and radiologic phenotypes, and long-term outcome.
Methods: By using consensus definitions and a retrospective single-center cohort of 164 Australian children, we performed clinical and radiologic phenotyping blinded to etiology and outcomes, and we tested archived acute sera for autoantibodies to N-methyl-D-aspartate receptor, voltage-gated potassium channel complex, and other neuronal antigens.
Background: In endemic areas, leptospirosis is more common and more severe in adults compared with children. Reasons to explain this discrepancy remain unclear and limited data focusing on adolescents are available. The objective of the study was to describe disease spectrum and outcome differences in children and adolescents admitted for leptospirosis in a large at-risk population.
View Article and Find Full Text PDFIn developed countries, Hansen disease, or leprosy, is a rare and little-known disease. Over the last few years, its prevalence in New Caledonia has remained stable (0.35 per 10,000 inhabitants).
View Article and Find Full Text PDFArticle Synopsis
- Autoimmune autonomic ganglionopathy (AAG) is a rare condition mainly affecting older adults, leading to widespread autonomic dysfunction.
- A case study highlights a 13-year-old girl experiencing severe symptoms such as gut issues, bladder problems, and unresponsive dilated pupils, with positive autoantibodies indicating an autoimmune condition.
- The girl initially did not improve with steroids but showed significant recovery after adding azathioprine to her treatment, showcasing that AAG can affect children and impact multiple organ systems.