Transient hydrops fetalis associated with intrauterine cytomegalovirus infection: prenatal diagnosis.

Background: Intrauterine cytomegalovirus infection is usually unrecognized during pregnancy. However, in some cases, ultrasound abnormalities can be observed in association with cytomegalovirus infection.

Case: The prenatal diagnosis of cytomegalovirus infection in a fetus with transient hydrops is reported.

Rapid detection of human cytomegalovirus viraemia from small volumes of heparinized whole blood.

Rapid detection of human cytomegalovirus (HCMV) from blood was performed in parallel using inoculation into human fibroblastic cells of both 500 microliters of whole blood and of buffy coat derived from 9.5 ml of blood. Of the 46 samples tested, 20 were positive for HCMV, 18 when the buffy coat was inoculated (90%) and 17 (85%) when whole blood was used.

Cytomegalovirus antigenemia assay: therapeutic usefulness and biological significance.

The cytomegalovirus antigenemia test is based on immunocytochemical detection of HCMV early structural protein pp65 in the nuclei of polymorphonuclear blood leucocytes of patients with systemic infection. Specificity and sensitivity are > or = 90% and positivity correlates well with HCMV disease, allowing better monitoring than isolation from buffy coat of patients undergoing chemotherapy. Polymorphonuclear cells appear as a main site of initial HCMV infection and reactivation.

[Chlamydia trachomatis: risk factors in women in the Parisian region. Importance of smoking and cervical ectropion].

A study of chlamydial infection and its clinical correlates was undertaken collaboratively among french women attending sexually transmitted disease (STD, prenatal, and teen clinics (n = 148). A complete sexual and gynecologic history and pelvic exam was performed on all women. Endocervical and urethral cultures were obtained for C.

[4 new cases of neuromyositis, one of them associated with HTLV-I infection].

Neuromyositis is a very rare type of polymyositis where, beside the usual muscular manifestations, there are signs of peripheral neuropathy which can be found at clinical, electromyographic and/or pathological examination. We have seen between 1983 and 1990 four cases of neuromyositis. The neurological disorder was an axonopathy in two cases which is usual in neuromyositis; in the other two cases, there was a polyradiculoneuritis which seems to be very rare in this syndrome.