Background: Febrile illness in returned travelers presents a diagnostic challenge in non-endemic settings. Chat generative pretrained transformer (ChatGPT) has the potential to assist in medical tasks, yet its diagnostic performance in clinical settings has rarely been evaluated. We conducted a preliminary validation assessment of ChatGPT-4o's performance in the workup of fever in returning travelers.
View Article and Find Full Text PDFChiral pincer complexes, characterized by their rigid tridentate coordination framework, have emerged as powerful catalysts in asymmetric synthesis. This review provides a comprehensive overview of recent advancements in the development of chiral pincer-type ligands and their corresponding transition metal complexes. We highlight the latest progress in their application across a range of catalytic asymmetric reactions, including the (transfer) hydrogenation of polar and non-polar bonds, hydrophosphination, alkynylation, Friedel-Crafts reactions, enantioselective reductive cyclization of alkynyl-tethered cyclohexadienones, enantioselective hydrosilylation, as well as Aza-Morita-Baylis-Hillman reactions.
View Article and Find Full Text PDFBackground: We describe an epidemiological investigation of a SARS-CoV-2-XBB.1 outbreak among healthcare workers (HCWs) returning from a 5-days educational tour abroad.
Methods: We prospectively followed participants for symptoms and sampled blood for neutralization assays of four SARS-CoV-2 variants (wild type, XBB, EG.
Correlates of protection for recent emerging SARS-CoV-2 variants have not been determined. In this test-negative case-control study, we report lower odds of infection with XBB variants among those boosted during the last six months. Additionally, we demonstrate that XBB-specific neutralizing antibodies are independent correlates of protection.
View Article and Find Full Text PDFIn our paper, we propose a generalized version of the Alternating Projections Digital Hard Successive Interference Cancellation (AP-HSIC) algorithm that is capable of decoding any order of constellation M in an M-Quadrature Amplitude Modulation (QAM) system. Our approach applies to Rayleigh deep-fading Multiple-Input Multiple-Output (MIMO) channels with high-level Additive White Gaussian Noise (AWGN). It can handle various destructive phenomena without restricting the number of antenna arrays in the transmitter/receiver.
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