Background: Behavioral and psychological symptoms of dementia (BPSD) occur frequently in persons with Alzheimer's disease (PAD). They cause suffering, institutionalization, carepartner distress, depression, burden, and decreased PAD-carepartner quality of life. Brexpiprazole approval advanced the AD treatment armamentarium.
View Article and Find Full Text PDFThe properties and device applications of 2D semiconductors are highly sensitive to intrinsic structural defects due to their ultrathin nature. CuInSe (CIS) materials own excellent optoelectronic properties and ordered copper vacancies, making them widely applicable in photovoltaic and photodetection fields. However, the synthesis of 2D CIS nanoflakes remains challenging due to the nonlayered structure, multielement composition, and the competitive growth of various by-products, which further hinders the exploration of vacancy-related optoelectronic devices.
View Article and Find Full Text PDFInflammatory bowel disease (IBD) is a multisystem condition that could affect the cutaneous systems, namely cutaneous extraintestinal manifestations (EIMs). It has been suggested that IBD is associated with erythema nodosum (EN), malignant melanoma (MM) and non-melanoma skin cancer (NMSC). However, the potential causal relationship between IBD and the mentioned above cutaneous EIMs is still unclear.
View Article and Find Full Text PDFMicro actuators are widely used in NEMS/MEMS for control and sensing. However, most are designed with suspended beams anchored at fixed points, causing two main issues: restricted actuated stroke and movement modes, and reduced lifespan due to fatigue from repeated beam deformation, contact wear and stiction. Here, we develop an electrostatic in-plane actuator leveraging structural superlubric sliding interfaces, characterized by zero wear, ultralow friction, and no fixed anchor.
View Article and Find Full Text PDF