Publications by authors named "Y P Goldberg"
Background: Valvular heart disease (VHD) is a major focus of cardiovascular medicine, but limited data are available for racial and ethnic minorities. The aim was to assess the burden and clinical correlates of VHD in a highly diverse area of the United States.
Methods And Results: Individuals with echocardiographic diagnosis of native VHD between January 2010 and December 2019 at a quaternary care health system of the Bronx (New York, USA) were included.
Over three years since the first identified SARS-CoV-2 case was discovered, the role of adolescents and children in spreading the virus remains unclear. Specifically, estimating the relative susceptibility of a child with respect to an adult is still an open question. In our work, we generalize a well-known household model for modeling infectious diseases, to include missing tests.
View Article and Find Full Text PDFDeciphering the spectrum and founder disease-causing variants (DCVs) in specific populations can shape and facilitate the diagnostic process of Lynch Syndrome (LS). The aim of this report was to comprehensively update on the genetic landscape of LS in the ethnically diverse Israeli-Jewish population. The cohort included 1080 carriers from 588 families; some from underrepresented, understudied Israeli ethnic groups recruited from 8 genetic institutes and high-risk clinics throughout the country.
View Article and Find Full Text PDFArticle Synopsis
- * A total of 587 patients were analyzed, with no significant differences in primary outcomes such as death or re-hospitalization at 1 month and 1 year between those with and without AI.
- * Results showed that two-thirds of patients with combined AI and MR experienced an improvement in AI severity post-procedure, suggesting that m-TEER can be an effective treatment option for high-risk patients dealing with both conditions.
Article Synopsis
- In 2023, public health policies transitioned from emergency responses to long-term COVID-19 management, creating challenges for routine booster campaigns amid uncertain seasonal patterns of the virus.
- A study focused on the first booster campaign in France during the 2021/2022 winter, utilized a multi-strain model to evaluate the effectiveness of booster vaccinations against Delta and Omicron variants.
- Results indicated that the immunization program's success heavily relied on including adults in eligibility and the timing of doses, revealing that even slight changes in inter-dose delay could necessitate significant social distancing measures to manage hospitalization peaks.