Predictive and prognostic nomogram models for liver metastasis in colorectal neuroendocrine neoplasms: a large population study.

Background: In recent years, the incidence of patients with colorectal neuroendocrine neoplasms (CRNENs) has been continuously increasing. When diagnosed, most patients have distant metastases. Liver metastasis (LM) is the most common type of distant metastasis, and the prognosis is poor once it occurs.

Orchestrated immune responses to Mycobacterium marinum natural infection in tongue sole (Cynoglossus semilaevis).

Mycobacterium marinum is a major pathogen in aquaculture, posing a substantial threat to the health and sustainability of tongue sole (Cynoglossus semilaevis) farming. This study investigated the genetic basis of immune response in tongue sole by comparing transcriptome profiles of liver and spleen tissues from symptomatic (susceptible) and healthy (resistant) individuals during a natural M. marinum outbreak.

Iridium(III) Blue Phosphors with Heteroleptic Carbene Cyclometalates: Isomerization, Emission Tuning, and OLED Fabrications.

Ir(III) complexes are particularly noted for their excellent photophysical properties in giving blue OLED phosphors. In this study, two distinctive carbene pro-chelates LAH2+ and LBH2+ (or LCH2+) were employed in preparation of heteroleptic Ir(III) complexes, to which LAH2+ bears a cyano substituted benzoimidazolium along with N-mesityl appendage, while LBH2+ (or LCH2+) carries the symmetrical benzoimidazolium entity. Notably, the reversible equilibration at high temperature was observed for m, f-ct14 and m, f-ct15 with a single LA chelate.