Publications by authors named "Y Oshiro"
Stage-specific embryonic antigen-4 (SSEA-4) is a developmentally regulated antigen, while expression level of SSEA-4 and / or its synthase ST3GAL2 is associated with prognosis in various malignancies. We have reported a prominent increase of SSEA-4 in castration-resistant prostate cancer (CRPC) and its negative correlation with the androgen receptor (AR). Meanwhile, loss of AR has increased to approximately 30% with the growing use of androgen receptor signaling inhibitor for metastatic CRPC (mCRPC).
View Article and Find Full Text PDFIntroduction: Proton beam therapy (PBT) may reduce the number of adverse events in treatment of patients with pediatric cancer. However, it is difficult to evaluate whether the actual therapeutic effect is truly equivalent to that of photon radiotherapy. To compare photon radiotherapy and PBT, a meta-analysis and systematic review were performed.
View Article and Find Full Text PDFArticle Synopsis
- Intraosseous hemangiomas are rare, benign tumors affecting bones, particularly the vertebrae and calvarium, which can cause complications like visual problems and deformities due to their slow growth.
- A case study of a 10-year-old girl with a recurring giant calvarial hemangioma demonstrated the use of proton beam therapy (PBT) after previous treatments failed, showing positive results.
- The patient tolerated the PBT well, with minor side effects, and after 14 months, there was a significant reduction in tumor size, suggesting PBT's potential as an effective treatment for difficult cases of hemangiomas in children.
Background: Spinal cord stimulation (SCS) is widely accepted as a useful treatment for patients with intractable chronic pain. However, its effectiveness varies between individuals. Therefore, a tool for evaluating its effectiveness in advance is eagerly awaited.
View Article and Find Full Text PDF