Raising Awareness for Sustainable Faecal Treatment Using Augmented Reality.

Pit latrines-the simplest on-site sanitation system-have been extensively used in developing countries in Asia for a long time. However, pit latrines are pollution and health risk hotspots that can cause widespread contamination. It is preferable to upgrade them to septic tanks, which are more advanced, effective, and simple alternatives.

Prevalence of Urinary Incontinence and Its Association With Neurodevelopmental Disorders Among Children in Japan.

Aim: To investigate urinary incontinence prevalence and its association with neurodevelopmental disorders among children in Japan.

Methods: A web-based survey was conducted on children aged 5-15 years in Japan. Information on daytime and nocturnal incontinence and neurodevelopmental disorders, such as attention deficit hyperactivity disorder, autism spectrum disorder, and intellectual disability, was collected.

Continuous Monitoring of Pseudopolymorphic Transition in Ezetimibe Using T Relaxation with Time-Domain NMR.

The purpose of this study was to continuously monitor the pseudopolymorphic transition from anhydrate to monohydrate by measuring the NMR relaxation using time-domain NMR (TD-NMR). Taking advantage of the simplicity of the low-field NMR instrument configuration, which is an advantage of TD-NMR, the NMR instrument was connected to a humidity controller to monitor the pseudopolymorphic transition. First, ezetimibe (EZT) monohydrate was prepared from its anhydrate using a saturated salt solution method, and T relaxation of EZT monohydrate and anhydrate was measured without a humidity controller.

The Uptake of Heparanase into Mast Cells Is Regulated by Its Enzymatic Activity to Degrade Heparan Sulfate.

Mast cells take up extracellular latent heparanase and store it in secretory granules. The present study examined whether the enzymatic activity of heparanase regulates its uptake efficiency. Recombinant mouse heparanase mimicking both the latent and mature forms (L-Hpse and M-Hpse, respectively) was internalized into mastocytoma MST cells, peritoneal cell-derived mast cells, and bone marrow-derived mast cells.