Publications by authors named "Y Omae"
Background: Thermal damage may lead to inflammation of the peeled mucosal surface during endoscopic submucosal dissection (ESD).
Aim: To determine the effect of Joule heat on the onset of post-ESD electrocoagulation syndrome (PECS).
Methods: In this prospective study, PECS was characterized by in-hospital fever (white blood cell count: ≥ 10000 μ/L or body temperature ≥ 37.
Purpose: Achromatopsia (ACHM) is an early-onset cone dysfunction caused by 5 genes with cone-specific functions (, , , and ) and by , a transcription factor with ubiquitous expression. To improve the relatively low variant detection ratio in these genes in a cohort of exome-sequenced Japanese patients with inherited retinal diseases (IRD), we performed genome sequencing to detect structural variants and intronic variants in patients with ACHM.
Methods: Genome sequencing of 10 ACHM pedigrees was performed after exome sequencing.
Article Synopsis
- The COVID-19 pandemic's spread is closely linked to human movement, leading researchers to explore factors influencing this flow, particularly in relation to vaccinations and regional characteristics.
- A study in Narashino City, Japan, utilized machine learning models, specifically LightGBM, to analyze how vaccination rates and infection numbers impact human flow patterns.
- The results suggest that before vaccinations, people's mobility was more influenced by infection rates in larger areas, while post-vaccination, local infection numbers may gain more focus, indicating a potential shift in public perception of risk.
Article Synopsis
- Tuberculosis caused by Mycobacterium tuberculosis (Mtb) remains a major global health concern, and this study introduces a new method to identify large genetic insertions and deletions (indels) that have been overlooked.
- The analysis of 1,960 Mtb clinical isolates shows that harmful genetic variants are rarely found in essential survival genes, while Mtb genomes contain many partially harmful mutations.
- The research also links specific genetic variations, including indels in various genes, to patient outcomes and antibiotic resistance, offering insights that could improve tuberculosis treatment and prediction of risks.