Publications by authors named "Y Oishi"
Nonspecific viral adsorption by polymer nanoparticles is more economical and superior in terms of operating cost and energy efficiency than viral adsorption using virus-specific antibodies and filtration techniques involving size exclusion in the order of tens of nanometres. In this study, we synthesised four types of polycyclic aromatic polymer (ArP) nanoparticles with different structures and evaluated their virus adsorption capability for infectious particles of the newly emerged severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). ArP nanoparticles with a diameter of approximately 500 nm were prepared by one-pot precipitation polymerisation using structural isomers of bifunctional dihydroxynaphthalene (1,5-dihydroxynaphthalene and 2,6-dihydroxynaphthalene) as phenol monomers, as well as 3-hydroxybenzoic acid and 3-aminophenol as comonomers to introduce carboxylic acid and amino groups, respectively.
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- * The patient had issues with his artificial aortic valve leading to severe stenosis, while his prosthetic mitral valve showed mild problems, prompting the fifth surgery to replace the aortic valve with a new bioprosthetic valve.
- * The report emphasizes the importance of managing eosinophil levels before and after surgery, alongside careful selection of artificial valves, to enhance treatment outcomes for patients with HES and related heart valve diseases.
Article Synopsis
- Enfortumab Vedotin (EV) is an effective treatment for advanced urothelial carcinoma (UC) patients who have already undergone other therapies, but there’s limited understanding of the factors that impact patient outcomes.
- A retrospective study was conducted to identify clinical factors affecting progression-free survival (PFS) and overall survival (OS) in these patients, leading to the development of a new risk classification model based on identified prognostic factors.
- The study found that high levels of C-reactive protein and hypercalcemia were significant predictors of patient outcomes, allowing for the classification of patients into three distinct risk groups, which showed notable differences in survival rates.
This study reveals the pH-responsive behavior of collagen hydrogels prepared using ultraviolet (UV) irradiation with riboflavin as a photosensitizer. By varying the UV exposure time, we modulated the crosslinking density, thereby influencing the mechanical properties and pH responsiveness. Rheological analysis confirmed successful network formation, whereas swelling studies revealed significant pH-dependent behavior, with maximum swelling at a pH of four and minimal swelling above a pH of six, demonstrating partial reversibility over multiple pH cycles.
View Article and Find Full Text PDFIntroduction: This study aimed to investigate the relationship between childbirth and lower back pain and determine the health-related quality of life of female patients with lower back pain.
Methods: A total of 111 patients were divided into three groups: those who had given birth and developed lower back pain due to pregnancy, childbirth, or child-rearing movements (childbirth group, n=41), those who had given birth and developed lower back pain due to other causes (childbirth and other cause group, n=29), and those who were nulliparous (nulliparous group, n=41). A total of 22 physical therapists evaluated the patients during initial rehabilitation.