Publications by authors named "Y O R Silva"
Efficacy and safety of tirofiban in acute ischemic stroke due to intracranial atherosclerotic disease for patients undergoing endovascular treatment: a systematic review and meta-analysis.
Luiz Fábio Silva Ribeiro Lucas Rezende de Freitas Ofonime Chantal Udoma-Udofa Júlia Dos Santos Monteiro Yasmin Picanço Silva
Neuroradiology
December 2024
Purpose: Tirofiban has emerged as an adjunct therapy for acute ischemic stroke (AIS) patients undergoing endovascular treatment (EVT). However, its benefits for AIS patients with intracranial atherosclerotic disease (ICAD) remains unclear. This meta-analysis evaluates its efficacy and safety in ICAD-related AIS patients undergoing EVT.
View Article and Find Full Text PDFCanine monocytic ehrlichiosis (CME) is an infectious disease caused by , a globally recognized obligate intracellular bacterium. In addition to dogs, other animals, including humans, may be affected. Despite its epidemiological importance and impact on public health, there is currently no commercial vaccine against .
View Article and Find Full Text PDFArticle Synopsis
- Hematoma expansion (HE) occurs in a significant portion of patients with acute intracerebral hemorrhage (ICH), impacting their outcomes; the study focuses on the predictive accuracy of the Black-&-White (B&W) sign in identifying HE.
- In a multicenter cohort from the PREDICT study, the association between the B&W sign and HE was analyzed, revealing that patients with the B&W sign had a higher frequency of HE and more substantial growth of hematomas compared to those without it.
- The B&W sign strongly predicts HE, with an adjusted odds ratio of 7.83 for HE and 5.67 for severe HE, indicating that its presence significantly increases the risk of hematoma expansion.
Article Synopsis
- Trema micranthum, a plant from the Cannabaceae family, shows potential as a new source of cannabinoids like CBD, amid the regulatory issues surrounding Cannabis sativa due to THC content.
- This study used advanced UHPLC-HRMS/MS techniques to analyze different parts of the plant—fruits, leaves, inflorescences, and stems—for the presence of CBD, THC, and their acidic precursors (THCA A and CBDA).
- The results revealed significant levels of cannabinoids, especially in the leaves (4.43 µg/g CBD, 1.05 µg/g THC), indicating that Trema micranthum could serve as a viable alternative source for cannabinoid research and production.