Publications by authors named "Y Nunez Fernandez"

Walnut (Juglans regia L.) is the primary nut tree cultivated in Chile, covering 44.626 ha.

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Purpose: Trans and gender diverse (TGD) people are one of the world's most marginalized populations. Current evidence indicates that ostracism faced by these communities leads to multiple adverse conditions. The synergistic impact of these conditions -a syndemic-has been well established among other marginalized populations.

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Two structurally unrelated small molecule chemotypes, represented by compounds PAV-617 and PAV-951, with antiviral activity in cell culture against Mpox virus (formerly known as monkeypox virus) and human immunodeficiency virus (HIV) respectively, were studied for anti-cancer efficacy. Each exhibited apparent pan-cancer cytotoxicity with reasonable pharmacokinetics. Non-toxicity is demonstrated in a non-cancer cell line and in mice at doses achieving drug exposure at active concentrations.

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Background: Desmoid tumors can cause morbidity due to local invasion, potentially being fatal when fast growth compromises vital structures. In this context, a timely treatment response is required. This study aims to compare the activity of sorafenib and anthracycline-containing regimens during the first year of treatment.

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