Publications by authors named "Y Noguchi"
Objective: Cardiac computed tomography (CT) helps screen coronary artery stenosis in cases with dilated cardiomyopathy (DCM). Extracellular volume fraction (ECV) analysis has recently been eligible for CT.
Method: We evaluated the impact of ECV on the CT to predict the prognosis in DCM patients with heart failure with reduced ejection fraction (HFrEF).
Article Synopsis
- The CDK4/6 inhibitor palbociclib often causes neutropenia, making it challenging to maintain the standard 3/1 dosing schedule (3 weeks on, 1 week off) for patients with hormone receptor-positive and HER2-negative metastatic breast cancer.
- A study conducted at Ogaki Municipal Hospital analyzed different dosing schedules and their impact on treatment duration, dose intensity, overall response rate, and adverse events among patients treated from January 2018 to November 2023.
- Results indicated that alternative dosing schedules (3/2 and 2/2) were associated with longer treatment durations and higher overall response rates compared to the standard 3/1 schedule, suggesting these alternatives may maintain therapeutic effectiveness.
Circulating CD34-positive cell count is inversely associated with height loss. It acts as an indicator of endothelial repair activity. In conjunction with CD34-positive cells, platelets contribute to endothelial repair.
View Article and Find Full Text PDFBmi1 is a polycomb protein localized in stem cells and maintains their stemness. This protein is also reported to regulate the expression of various differentiation genes. In this study, to analyze the role of Bmi1 during dentinogenesis, we examined the immunohistochemical localization of Bmi1 during rat tooth development as well as after cavity preparation.
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