Publications by authors named "Y Niv"
Article Synopsis
- Bismuth quadruple therapies (BQTs) have been effective in treating Helicobacter pylori infections in Europe, particularly in the face of antibiotic resistance, with notable use increasing from 8.6% in 2013 to 39% in 2021.
- An analysis of data from nearly 50,000 patients indicated that the single-capsule BQT was the most common regimen and achieved over 90% effectiveness with certain combinations.
- Key factors that improved treatment success included adherence to the regimen, use of high-dose proton pump inhibitors, and implementing the therapy as a first-line treatment.
Article Synopsis
- Recent studies on potassium-competitive acid blockers (P-CABs) for treating Helicobacter pylori infections reveal a lack of network meta-analysis (NMA) comparing different P-CAB-based treatment regimens for their effectiveness and safety.
- A Bayesian NMA was conducted involving 25 randomized controlled trials with over 7,600 patients, comparing P-CAB and PPI therapies across dual, triple, and quadruple strategies.
- The results indicated that P-CAB dual therapy was the most effective treatment with the best safety profile, highlighting its advantage over traditional methods, particularly in addressing issues like clarithromycin resistance.
Estrogen receptor beta (ERβ) in esophageal cancer - a systematic review and meta-analysis.
Scand J Gastroenterol
October 2024
Background: Esophageal cancer is the eighth most common cause of cancer-related deaths worldwide. There are two main histological subtypes of esophageal cancer: adenocarcinoma and squamous cell carcinoma. Among the factors associated with the development of esophageal cancer, estrogen receptor beta (ERβ) has been found to have a clinical significance.
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