Publications by authors named "Y Nishita"

Background: While previous literature suggests that multimorbidity is linked to a higher risk of mortality, evidence is scarce among individuals in middle adulthood. We aimed to examine the association between physical multimorbidity and all-cause mortality among individuals aged 40-64 years at baseline in Japan.

Methods: Data were obtained from two cohort studies, the Japan Public Health Center-based Prospective Study (JPHC) and the Japan Epidemiology Collaboration on Occupational Health Study (J-ECOH).

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Article Synopsis
  • The study investigated the link between long-term statin use and sarcopenia, muscle strength, and physical performance among elderly individuals.
  • Participants aged 40 and older in Japan were analyzed, comparing those on statins to a matched control group not using statins.
  • Methods included a population-based cohort design and statistical analysis to evaluate outcomes like muscle mass, strength, and performance according to established sarcopenia criteria.
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Objectives: Variability in intrinsic capacity (IC) changes among community-dwelling older adults and their effect on health outcomes remain understudied. We examined the variability in IC trajectories and their impact on higher-level functional capacity (HLFC), life satisfaction, and self-esteem.

Design: Longitudinal study.

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Considering that a multifactorial lifestyle approach may prove more effective than a single factor approach to improve or maintain brain health, we evaluated the association of exercise (open skill exercise [OSE] or closed skill exercise [CSE]) combined with long-chain polyunsaturated fatty acid (LCPUFAs) (docosahexaenoic acid [C22:6n-3, DHA], eicosapentaenoic acid [C20:5n-3, EPA], and arachidonic acid [C20:4n-6, ARA]) intake with brain atrophy among older Japanese individuals (n = 795, aged 60-88 years) without a self-reported history of dementia based on the datasets of a two-year longitudinal study. Brain volumes were measured using three-dimensional T1-weighted brain magnetic resonance imaging for follow-up periods of two years. The associations between multivariate-adjusted changes in brain volumes and OSE or CSE frequency (≥ once/month and < once/month) along with LCPUFA intake (≥ median and < median) at the baseline were assessed using a general linear model.

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