Publications by authors named "Y Nishiguchi"

Introduction: Paranoid ideation, a crucial component of psychotic-like experiences, tends to increase between early and late adolescence, even in the general population, and it negatively affects overall mental health and social adjustment. Japanese adolescents experience high levels of interpersonal stress. However, few studies have examined the relationship between paranoid ideation and interpersonal stress.

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Introduction: Patients with Parkinson's disease (PD) may benefit from deep brain stimulation (DBS). Perifocal brain edema sometimes occurs after DBS surgery, but it is transient and does not affect the final prognosis. Transient deterioration of cognitive function has been reported in patients with frontal edema in the first postoperative week.

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Article Synopsis
  • The study aimed to determine how the CALLY index impacts patients with gastric cancer who have undergone gastrectomy, using data from 617 patients treated between 2014 and 2020 at Osaka City General Hospital.
  • Researchers calculated the CALLY index using a specific formula and compared it to other biomarkers to assess its predictive value for patient outcomes.
  • Results indicated that the CALLY index had the highest predictive value for overall survival and cancer-specific survival rates, making it a significant indicator for major complications in these patients.
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β-Casomorphin-7 (BCM), a breakdown product of milk β-casein, exhibits opioid activity. Opioids are known to affect the immune system, but the effects of BCM on ulcerative colitis (UC) are not clear. We examined the effects of BCM on mucosal immunity using a mouse dextran sulfate sodium-induced colitis model and an in vitro CD8+ T cell activation model.

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  • The study developed and validated a Japanese version of the State Optimism Measure (J-SOM) to assess fluctuations in optimism among individuals over time.
  • The research found significant correlations between state optimism, mood, and daily life quality, indicating that optimism can change more frequently than previously thought.
  • Results showed that state optimism fluctuates more than trait optimism over several weeks and that these changes are linked to mental health factors like depressive mood and subjective happiness.
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