[Breathing disorders during sleep in patients with dystrophic myotonia].

Objective: To analyze the results of nocturnal breathing parameters during sleep based on nocturnal pulse oximetry and to study of characteristics of external respiration in genetically confirmed patients with dystrophic myotonia (DM).

Material And Methods: The subjects of the study were patients with genetically confirmed DM types 1 and 2 who were hospitalized in the neurological departments of the Republican Scientific and Practical Center for Neurology and Neurosurgery. The clinical picture of the disease, comorbidities, sleep questionnaires, laboratory tests, overnight pulse oximetry and spirometry were performed and analyzed.

[Non-invasive ventilation of the lungs in neuromuscular diseases].

Objective: To describe a clinical case and to analyze our own practice of using NIVL in a myasthenia (MG) gravis patient.

Material And Methods: Since 2018 in the Republican Research and Clinical Center of Neurology and Neurosurgery NIVL has been performed in 29 patients (21 amyotrophic lateral sclerosis patients and 8 MG patients). The research was carried out using the portable polysomnograph Polymate YH-1000C (BMC, China) and in the Sleep Laboratory of the Republican Clinical Medical Center of the Presidential Administration of the Republic of Belarus using SOMNOlab V 2.

[Psychogenically induced narcolepsy].

Based on own clinical experience in diagnostics and treatment of 4 patients, the authors describe main clinical presentations of narcolepsy. A case report of a 20-year female patient with psychogenic narcolepsy induced by a conflict in the family is described in details. According to polysomnography and Multiple Sleep Latency Test, a reduction in latency to sleep is 22 sec - 3 min 30 sec and the time of occurrence of REM sleep is 7 min 30 sec.

[Sleep-disordered breathing in motor neuron disease].

Aim: To study sleep-disordered breathing (SDB) in patients with motor neuron disease (MND).

Material And Methods: Ninety-two patients, 50 women and 42 men, were examined Median age was 62 [55; 67.5] years, MND duration 12 [8.

[Neurospecific proteins in cerebrospinal fluid and in the bloodserum of patients with amyotrophic lateral sclerosis].

Aim: To determine concentrations of neurospecific enolase (NSE) and S100b protein in bloodserum and cerebrospinal fluid (CSF) in patients with amyotrophic lateral sclerosis (ALS) with different forms (onset) and duration of ALS.

Material And Methods: Concentrations of NSE and S100b in serum and CSF were studied in 86 patients with different forms and duration of ALS.

Results And Conclusion: Concentrations of NSE and S100b protein in CSF were significantly higher in the group of patients with bulbar form and in the group with duration of disease less than 1 year compared to the control group.