Distinct CSF α-synuclein aggregation profiles associated with Alzheimer's disease phenotypes and MCI-to-AD conversion.

Background: α-Synuclein (α-Syn) pathology is present in 30-50 % of Alzheimer's disease (AD) patients, and its interactions with tau proteins may further exacerbate pathological changes in AD. However, the specific role of different aggregation forms of α-Syn in the progression of AD remains unclear.

Objectives: To explore the relationship between various aggregation types of CSF α-Syn and Alzheimer's disease progression.

Rethinking the biochar impact on the anaerobic digestion of food waste in bench-scale digester: Spatial distribution and biogas production.

The improvement of biogas production in anaerobic digestion (AD) by biochar introduction has been demonstrated. However, the distribution of biochar in the digester and its effect on AD have been seldom explored. In this study, the distribution of biochar and their impact on AD were investigated in a 30 L semi-continuously operated bench-scale anaerobic digester.

Spatial and temporal distribution patterns and conservation status of seagrasses in the Yellow Sea and Bohai Sea.

Seagrasses represent a significant class of marine foundation species, yet the distribution of seagrasses in the Yellow Sea and Bohai Sea remains uncertain, thereby impeding the efficacy of conservation and restoration practices. In this study, the spatial and temporal distribution pattern of seagrasses was simulated by the MaxEnt model based on the construction of marine environment and human activity datasets. The main controlling factors affecting seagrass potential distribution were analyzed, and the response of seagrass distribution to global change was clarified.

Two pathogen-inducible UDP-glycosyltransferases, UGT73C3 and UGT73C4, catalyze the glycosylation of pinoresinol to promote plant immunity in Arabidopsis.

UDP-glycosyltransferases (UGTs) constitute the largest glycosyltransferase family in the plant kingdom. They are responsible for transferring sugar moieties onto various small molecules to control many metabolic processes. However, their physiological significance in plants is largely unknown.