Publications by authors named "Y Meije"
Article Synopsis
- - The study aimed to determine if using multiplex real-time PCR combined with conventional microbiological testing is safer and more effective in reducing antibiotic use for community-acquired pneumonia (CAP) compared to just conventional testing alone.
- - A total of 242 hospitalized adults with CAP participated in a randomized trial across four Spanish hospitals, where they were assigned to either the combined testing method or conventional testing only.
- - Results showed that the median days of antibiotic therapy were slightly lower in the multiplex PCR group but not significantly so, and both methods had similar rates of adverse events and 30-day mortality, suggesting that the combined approach should not be routinely implemented.
Aims: To assess sensory neuropathy development after severe COVID-19.
Methods: Patients with severe COVID-19 underwent assessment of neuropathic symptoms, tendon reflexes, and quantitative sensory testing to evaluate vibration (VPT), cold (CPT), warm (WPT) and heat perception thresholds (HPT) within 1-3 weeks of admission and after 1-year.
Results: 32 participants with severe COVID-19 aged 68.
Article Synopsis
- The study investigates whether antibiotic therapy is necessary for low-risk catheter-related bloodstream infections (CRBSI) caused by coagulase-negative staphylococci (CoNS) after catheter removal.
- Conducted in 14 Spanish hospitals, the trial randomized 27 patients—15 received no antibiotics while 12 received standard antibiotic treatment—focusing on complications and recovery time over 90 days.
- Results showed that one patient in the non-antibiotic group developed a complication, suggesting that low-risk CRBSI due to CoNS might be safely managed without antibiotics, although the trial was halted due to low participant numbers.
(1) Background: Information regarding gene expression profiles and the prognosis of community-acquired pneumonia (CAP) is scarce. We aimed to examine the differences in the gene expression profiles in peripheral blood at hospital admission between patients with CAP who died during hospitalization and those who survived. (2) Methods: This is a multicenter study of nonimmunosuppressed adult patients who required hospitalization for CAP.
View Article and Find Full Text PDFIntroduction: Methicillin-susceptible (MSSA) bacteraemia is a frequent condition, with high mortality rates. There is a growing interest in identifying new therapeutic regimens able to reduce therapeutic failure and mortality observed with the standard of care of beta-lactam monotherapy. In vitro and small-scale studies have found synergy between cloxacillin and fosfomycin against .
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