Publications by authors named "Y Matsumi"
Objective: Trifluridine/tipiracil (FTD/TPI) is one of the options for late-line treatment of colorectal cancer (CRC). However, the specific patient populations that would particularly benefit from it remain unclear. This study attempted to identify predictive markers of chemotherapy efficacy with trifluridine/tipiracil (FTD/TPI), focusing on the RNA-editing enzyme adenosine deaminase acting on RNA 1 (ADAR1) expression and neutrophil-lymphocyte ratio (NLR).
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- The study focuses on the relationship between preoperative nutritional status and outcomes in colorectal cancer patients aged 75 and older, evaluating 71 patients who underwent surgery from July 2020 to September 2022.
- Patients were categorized using the Subjective Global Assessment (SGA) into well-nourished and varying levels of malnourished groups, finding correlations between nutritional status and postoperative results.
- The results indicated that malnourished patients (SGA-B/C) had higher ICU admissions, longer hospital stays, and significantly lower 3-year overall survival rates compared to well-nourished patients (SGA-A), highlighting the importance of assessing nutrition in older surgical patients.
A minimally invasive approach using laparoscopy or robotics has become the standard procedure in surgery for colorectal cancer. However, obesity is considered to be associated with a poor prognosis in laparoscopic colorectal surgery. Perioperative management, as well as the surgical procedure, is particularly important in severely obese patients.
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- Carbon fiber-reinforced plastics (CFRP) are strong and lightweight materials, but their processing generates harmful fibrous debris and fine particles.
- A study in a Japanese factory used advanced monitoring devices to assess particle generation and worker exposure during CFRP processing operations like cutting and grinding.
- Results showed that the wearable P-sensor effectively detected smaller particles, and implementing better exhaust practices significantly reduced worker exposure to micro/nano particles.
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- Myeloid sarcoma (MS) is a rare tumor composed of immature myeloid cells, often linked to acute myeloid leukemia, but can occur independently, as seen in a case from a 33-year-old female with no previous medical history.
- The patient experienced abdominal pain and was diagnosed after surgery, which revealed an ileal tumor instead of suspected endometriosis, leading to a confirmed diagnosis of primary ileal MS without evidence of leukemia in the bone marrow.
- Appropriate surgical intervention not only provided a correct diagnosis but also paved the way for timely chemotherapy, highlighting the importance of proper surgical approaches in unusual cases like small bowel MS.