Publications by authors named "Y Likar"

Purpose: This study aimed to evaluate the ability of 18 F-FDG PET/CT metabolic parameters to predict the histological response to neoadjuvant chemotherapy in patients with osteosarcoma and Ewing sarcoma.

Patients And Methods: This systematic review and network meta-analysis adhered to the PRISMA-NMA and Cochrane guidelines. Electronic databases were searched from January 2008 to January 2024; this search was supplemented by snowballing methods.

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Background: Hodgkin lymphoma (HL) in pediatric populations has a high survival rate but poses risks for long-term morbidities. Although [F]fluoro‑2‑deoxy‑2‑d‑glucose positron emission tomography ([F]FDG PET) scans offer potential for improved risk stratification, the definitive prognostic value of quantitative [F]FDG PET parameters remains unclear for pediatric HL.

Methods: A single-center, retrospective study included pediatric patients diagnosed with HL between 2016 and 2023 treated according to EuroNet-PHL-C1 and DAL/GPOH-HD protocols.

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Purpose: The risk of posthepatectomy liver failure (PHLF) remains an important concern following major liver resection. Assessment of future remnant liver function (FRLF) by hepatobiliary scintigraphy has shown its significance to prevent PHLF after major liver resection in adults with a threshold value of FRLF greater than 2.7%/min per m2.

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Article Synopsis
  • Primary neuroblastoma is the most common solid tumor outside the brain in children, often found in the abdomen, particularly the adrenal glands.
  • * It can also occur in the thoracic region, especially in the posterior mediastinum.
  • * This text discusses a rare case of primary neuroblastoma located in the thymus of a pediatric patient.
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Background: In recent years, many research groups have attempted to identify a subgroup of "ultra-high risk" patients within the high-risk neuroblastoma (NB) category. The aim of our study was to evaluate the prognostic significance of parameters derived from pretherapeutic I-meta-iodobenzylguanidine ([ I]mIBG) integrated single photon emission computed tomography and computed tomography in high-risk patients with NB.

Methods: The established parameters metabolic tumor volume (MTV), maximal standardized uptake value (SUV ) and the novel parameter tumor asphericity as well as clinical (age, stage) and genetic factors (1p/11q deletions and MYCN amplification) were analyzed in this single-center retrospective study of high-risk patients with newly diagnosed NB.

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