Publications by authors named "Y Leonov"

Introduction: For patients on prolonged mechanical ventilation (PMV; > 21 days), successful weaning has been attributed to various factors. The aim of this study is to determine the usefulness of the rapid shallow breathing index(RSBI) and other potential predictors of successful weaning in patients unable to wean and requiring extreme PMV at a hospital-based long-term ventilator facility in Israel. Material and ethods: Retrospective analysis of prospectively collected data over 5 years.

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Article Synopsis
  • The study analyzed 100 adult patients with Guillain-Barré syndrome (GBS) from 2006 to 2018, finding that a significant 46.8% exhibited an axonal pattern in their EMG results.
  • A majority (58%) of those who initially presented with mild symptoms experienced a deterioration in their condition, with several losing the ability to walk independently.
  • The research concluded that a higher incidence of axonal GBS was observed in Israel compared to European and North American cohorts, and emphasized the need for prompt treatment following a GBS diagnosis due to the disease's progressive nature.
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Background: Use of TPA to treat patients with acute ischemic stroke was introduced in Assaf Harofeh Medical Center (AHMC) in Israel in November 2007 initially with strict adherence to the inclusion/exclusion criteria of the pivotal NINDS TPA studies published in 1995. The treatment window was expanded in 2010 to 4.5h following the results of ECASS-III.

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Background: The role of routine active surveillance cultures (ASCs) in predicting consequent bloodstream infections is unclear.

Objectives: To determine prospectively whether routine screening ASCs obtained on admission to the intensive care unit (ICU) can predict the causative agent of subsequent bloodstream infections.

Methods: We prospectively studied a cohort of 100 mechanically ventilated patients admitted consecutively to a 16-bed ICU.

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Background: Enteral nutrition in the critically ill patient is often complicated by gastrointestinal intolerance, manifested by a large gastric residual volume. The frequency of GRV assessment and the intolerant level above which feeding is stopped is controversial.

Objectives: To evaluate a novel approach to EN by allowing high GRV and once-daily assessment that was correlated with the paracetamol absorption test.

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