Publications by authors named "Y Le Corroller"

The target of this survey carried out in Guadeloupe (F.W.I.

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The authors appreciate the prevalence of drepanocytosis in a supposed healthy group of blood donors at the Transfusion Center. They propose to carry out a systematic detection of the various hemoglobin types existing in the isle at all stages of active-life: birth, school-time, prenatal consultations, controls for enrolment in the army, etc. They describe the action of the "mother and child protection service" which could develop information and genetic advice to try to limit the dissemination of the drepanocytic tract as well as to avoid the birth of homozygotes.

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The clinical, hematologic and biochemical study of three children, carriers of the double heterozygotous SN Baltimore hemoglobin from Guadeloupe, have not allowed to detect any typical anomaly and specially no sign of anemia or hemolysis. An iron deficiency of parasitologic origin has only been detected. This absence of pathological symptoms is related to the fact that SN red cells tend to sickle less rapidly than those from persons with sickle cell trait AS.

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The detection of hemoglobin AN Baltimore in a young man, 28 years old in June 1978, led us make a family study. This family study was very interesting because our proband had 16 brothers and sisters, many of whom also had many children. Research on abnormal hemoglobins was done on 46 family members: 28 were carriers of hemoglobin AN Baltimore and three children, carriers of heterozygote SN Baltimore.

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