CONSTITUTIONAL AND LEGAL PRINCIPLES OF THE LIMITS OF PERMISSIBLE INTERVENTION IN CONDUCTING BIOMEDICAL RESEARCH WITH HUMAN PARTICIPATION.

Objective: The aim: To find out the peculiarities of constitutional and legal principles of the limits of permissible intervention in conducting biomedical research with human participation.

Patients And Methods: Materials and methods: The methodological basis of the study was worldview dialectical, general scientific and specific scientific methods of learning the phenomena of state and legal reality. Common ones were widely used in the work principles of scientific knowledge - comprehensiveness, objectivity, historicism, unity of theory and practice and others.

ASSESSMENT OF THE IMPACT OF ANTIREFLUX THERAPY ON THE COURSE OF CHRONIC OBSTRUCTIVE PULMONARY DISEASE.

Objective: The aim: To examine the effect of antireflux therapy on the course of COPD.

Patients And Methods: Materials and methods: Under observation were 60 patients who were hospitalized in the «Transcarpathian Regional Clinical Hospital named after Andrei Novak» with a diagnosis of COPD II gr B in combination with GERD and 36 patients diagnosed with GERD who were treated on an outpatient basis. To study the effectiveness of antireflux therapy and its impact on the course of COPD, patients are divided into 2 groups: 1 group (main) (n = 60) - patients with COPD in combination with GERD, group 2 (control) (n = 36) - patients with isolated GERD.

THE EFFECTIVENESS OF COMPLEX THERAPY WITH THE INCLUSION OF THE URSODEOXYCHOLIC ACID IN PATIENTS WITH NON-ALCOHOLIC FATTY LIVER DISEASE IN COMBINATION WITH CHRONIC OBSTRUCTIVE PULMONARY DISEASE.

Objective: The aim: Was increase the effectiveness of treatment in patients with non-alcoholic fatty liver disease (NAFLD) comorbid with chronic obstructive pulmonary disease (COPD) by using ursodeoxycholic acid (UDCA) in combination with ademethionine.

Patients And Methods: Materials and methods: Under observation was 98 patients with a diagnosis of NAFLD and COPD group II or their combination. Patients were divided into 3 groups: 1 (n = 36) - COPD + NASH - in addition to standard COPD therapy received UDCA 15 mg / kg / day - 6 months and ademethionine 1000 mg IV once a day for 10 days, followed by oral administration of 500 mg 2 times per day - 20 days, and group 2 (n = 32) - COPD + hepatic steatosis - in addition to standard therapy - UDCA 15 mg / kg / day - 6 months.

CONVERSION THERAPY BANS IN NATIONAL LEGISLATIONS AROUND THE GLOBE.

The article summarizes the data on the number of conversion therapy legal bans aimed at changing sexual orientation and gender identity in countries around the globe; the content and the form of such prohibitions, the scope of their action by territorial criterion and the nature of the prohibition itself are analyzed; the draft laws, which are intended to legalize such bans in the national and territorial regime are studied; the thematic case law of individual countries is partly examined; countries where conversion therapy is promoted and explicitly authorized by public authorities are considered. According to the results of the study of more than half a hundred legal documents, the information obtained is distributed and organized into the following categories: national and regional prohibition of conversion therapy, direct and non-direct prohibition of conversion therapy; ban in different parts of the world. The content highlights the characteristics of the existing prohibitions, such as the name of the delict; year of entry into force of the relevant legal act; prohibition of sexual orientation and/or gender identity activities; the circle of persons subjected to the prohibition; the circle of persons protected by the prohibition; peculiarities.